台灣大學91學年第二學期
開課系所： 化學系
課程名稱： 物理化學下
課程編號： 203 33102 01/02
授課對象： 農化系
授課老師：陳逸聰教授

物理化學 課程大綱

一、 內容
6. Molecular Motion and Transport Properties
6.1 Concepts
6.2 Applications
6.3 Kinetic Theory
6.4 Molecular Collisions
6.5 Mean Free Path
6.6 Diffusion
6.7 Sedimentation
6.8 Determination of Molecular Weights from Sedimentation and Diffusion
6.9 Viscosity
6.10 Electrophoresis
6.11 Size and Shape of Macromolecules

7. Kinetics: Rates of Chemical Reactions
7.1 Concepts
7.2 Applications
7.3 Kinetics
7.4 Reaction Mechanisms and Rate Laws
7.5 Temperature Dependence
7.6 Transition-State Theory
7.7 Electro Transfer Reactions: Marcus Theory
7.8 Ionic Reactions and Salt Effects
7.9 Isotopes and Stereochemical Properties
7.10 Very Fast Reactions
7.11 Diffusion-Controlled Reactions
7.12 Photochemistry and Photobiology
7.13 Photosynthesis

8. Enzyme Kinetics
8.1 Concepts
8.2 Applications
8.3 Enzyme Kinetics
8.4 Michaelis-Menten Kinetics
8.5 Competition and Inhibition

9. Molecular Structures and Interactions: Theory
9.1 Concepts
9.2 Applications
9.3 The Process of Vision
9.4 Origins of Quantum Theory
9.5 Quantum Mechanical Calculations
9.6 Schrodinger’s Equation
9.7 Particle in a Box
9.8 Tunneling
9.9 Simple Harmonic Oscillator
9.10 Rigid Rotator
9.11 Hydrogen Atom
9.12 Electron Distribution
9.13 Molecular Structures and Molecular Orbitals
9.14 Intermolecular and Intramolecular Forces
9.15 Noncovalent Interactions
9.16 Molecular Dynamics Simulation

10. Molecular Structures and Interactions: Spectroscopy
10.1 Concepts
10.2 Applications
10.3 Electromagnetic Spectrum
10.4 Color and Refractive Index
10.5 Absorption and Emission of Radiation
10.6 Proteins and Nucleic Acids: Ultraviolet Absorption Spectra
10.7 Fluorescence
10.8 Optical Rotatory Dispersion and Circular Dichroism
10.9 Circular Dichroism of Nucleic Acids and Proteins
10.10 Vibrational Spectra, Infrared Absorption, and Raman Scattering
10.11 Nuclear Magnetic Resonance
10.12 Interactions in Nuclear Magnetic Resonance

11. Molecular Distributions and Statistical Thermodynamics (Optional)
11.1 Concepts
11.2 Applications
11.3 Binding of Small Molecules by a Polymer
11.4 The Random Walk
11.5 Helix-Coil Transitions
11.6 Statistical Thermodynamics

12. Macromolecular Structure and X-Ray Diffraction (Optional)
12.1 Concepts
12.2 Applications
12.3 Visible Images
12.4 X Rays
12.5 Determination of Molecular Structure
12.6 Electron Diffraction
12.7 Neutron Diffraction
12.8 Electron Microscopy

二、 教科書
書名：Physical Chemistry-Principles and Applications in Biological Sciences (Forth Edition)

作者： I. Tinoco, K. Sauer, J. C. Wang and J. D. Puglisi

三、 成績評量方式
依學校規定，以出席率、小考、期中考、期末考為依據


Ps.第一學期課程大綱
* Introduction (簡介)
* The First Law: Energy Is Conserved (第一定律：能量守恆)
* The Second Law: The Entropy of the Universe Increases (第二定律：宇宙之熵增加)
* Free Energy and Chemical Equilibria (自由能與化學平衡)
* Free Energy and Physical Equilibria (自由能與物理平衡)
* Molecular Motion and Transport Properties (分子運動與輸送性質)